Evidence

On this page, you can find an overview of Cochrane reviews that are relevant to the field of first aid. This includes not only reviews targeted at laypeople as providers of healthcare interventions, but also reviews that investigate interventions that are feasible in a lay setting.

The relevant reviews are structured according to the lay-out of a typical first aid manual, which tries to group conditions broadly according to body part (e.g. ear pain is covered in the chapter head), in addition to some specific conditions which do not necessarily fit within a specific region (e.g. bites and stings is a separate chapter).

Have you spotted first aid-relevant Cochrane reviews that are not on this list yet? Contact us, so we can add them.

Resuscitation and defibrillation     

                    

AuthorYearTitleCochrane Review Group
Barry2019Community first responders for out‐of‐hospital cardiac arrest in adults and childrenCochrane Emergency and Critical Care Group
Bruschettini2017Sustained versus standard inflations during neonatal resuscitation to prevent mortality and improve respiratory outcomesCochrane Neonatal Group
Huang2014Cardiopulmonary resuscitation (CPR) plus delayed defibrillation versus immediate defibrillation for out‐of‐hospital cardiac arrestCochrane Emergency and Critical Care Group
Lafuente-Lafuente2013Active chest compression‐decompression for cardiopulmonary resuscitationCochrane Heart Group
Zhan2017Continuous chest compression versus interrupted chest compression for cardiopulmonary resuscitation of non‐asphyxial out‐of‐hospital cardiac arrestCochrane Emergency and Critical Care Group


Bleeding

AuthorYearTitleCochrane Review Group
Robertson2016Vascular closure devices for femoral arterial puncture site haemostasisCochrane Vascular Group


Skin wounds

AuthorYearTitleCochrane Review Group
Dat2012Aloe vera for treating acute and chronic woundsCochrane Wounds Group
Fernandez2012Water for wound cleansingCochrane Wounds Group
López-Alcade2015Gloves, gowns and masks for reducing the transmission of meticillin‐resistant Staphylococcus aureus (MRSA) in the hospital settingCochrane Wounds Group
Reddy2017Devices for preventing percutaneous exposure injuries caused by needles in healthcare personnelCochrane Work Group
Vincent2016Disposable surgical face masks for preventing surgical wound infection in clean surgeryCochrane Wounds Group


Burns

AuthorYearTitleCochrane Review Group
Jull2015Honey as a topical treatment for woundsCochrane Wounds Group
Norman2017Antiseptics for burnsCochrane Wounds Group


Head and neck

AuthorYearTitleCochrane Review Group
Derry2013Paracetamol (acetaminophen) with or without an antiemetic for acute migraine headaches in adultsCochrane Pain, Palliative and Supportive Care Group
Derry2013Diclofenac with or without an antiemetic for acute migraine headaches in adultsCochrane Pain, Palliative and Supportive Care Group
Derry2015Ibuprofen for acute treatment of episodic tension‐type headache in adultsCochrane Pain, Palliative and Supportive Care Group
Derry2017Aspirin for acute treatment of episodic tension‐type headache in adultsCochrane Pain, Palliative and Supportive Care Group
Huang2012Chinese medicinal herbs for sore throatCochrane Acute Respiratory Infections Group
Kendrick2012Home safety education and provision of safety equipment for injury preventionCochrane Injuries Group
Kirthi2013Aspirin with or without an antiemetic for acute migraine headaches in adultsCochrane Pain, Palliative and Supportive Care Group
Lindsley2017Non‐surgical interventions for acute internal hordeolumCochrane Eyes and Vision Group
Lim2016Patching for corneal abrasionCochrane Eyes and Vision Group
Liu2008Helmets for preventing injury in motorcycle ridersCochrane Injuries Group
Patel2012Massage for mechanical neck disordersCochrane Back and Neck Group
Pucker2016Over the counter (OTC) artificial tear drops for dry eye syndromeCochrane Eyes and Vision Group
Rabbie2013Ibuprofen with or without an antiemetic for acute migraine headaches in adultsCochrane Pain, Palliative and Supportive Care Group
Sjoukes2016Paracetamol (acetaminophen) or non‐steroidal anti‐inflammatory drugs, alone or combined, for pain relief in acute otitis media in childrenCochrane Acute Respiratory Infections Group
Stephens2016Paracetamol (acetaminophen) for acute treatment of episodic tension‐type headache in adultsCochrane Pain, Palliative and Supportive Care Group
Thompson1999Helmets for preventing head and facial injuries in bicyclistsCochrane Injuries Group
Tikka2017Interventions to prevent occupational noise‐induced hearing lossCochrane Work Group
Yang2015Mailuoning for acute ischaemic strokeCochrane Stroke Group
Zhelev2019Prehospital stroke scales as screening tools for early identification of stroke and transient ischemic attackCochrane Stroke Group


Chest

AuthorYearTitleCochrane Review Group
Barker 2013Breathing exercises for dysfunctional breathing/hyperventilation syndrome in childrenCochrane Airways Group
Cates2013Holding chambers (spacers) versus nebulisers for beta‐agonist treatment of acute asthmaCochrane Airways Group
Donnelly2006Indoor air modification interventions for prolonged non‐specific cough in childrenCochrane Airways Group
Holland2012Breathing exercises for chronic obstructive pulmonary diseaseCochrane Airways Group
Jefferson2011Physical interventions to interrupt or reduce the spread of respiratory virusesCochrane Infectious Diseases Group
Jones2013Breathing exercises for dysfunctional breathing/hyperventilation syndrome in adultsCochrane Airways Group
Oduwole2018Honey for acute cough in childrenCochrane Acute Respiratory Infections Group
Rodriguez-Martinez2008Commercial versus home-made spacers in delivering bronchodilator therapy for acute therapy in childrenCochrane Airways Group
Smith2014Over‐the‐counter (OTC) medications for acute cough in children and adults in community settingsCochrane Acute Respiratory Infections Group
Wang2014Symptomatic treatment of the cough in whooping coughCochrane Acute Respiratory Infections Group


Stomach and back

AuthorYearTitleCochrane Review Group
Afshar2015Nonsteroidal anti‐inflammatory drugs (NSAIDs) and non‐opioids for acute renal colicCochrane Kidney and Transplant Group
Clasen2005Interventions to improve water quality for preventing diarrhoeaCochrane Infectious Diseases Group
Das2018Fly control to prevent diarrhoea in childrenCochrane Infectious Diseases Group
Ejemot-Nwadiaro2015Hand washing promotion for preventing diarrhoeaCochrane Infectious Diseases Group
Gregorio2016Polymer‐based oral rehydration solution for treating acute watery diarrhoeaCochrane Infectious Diseases Group
Hahn2002Reduced osmolarity oral rehydration solution for treating dehydration caused by acute diarrhoea in childrenCochrane Infectious Diseases Group
Hartling2006Oral versus intravenous rehydration for treating dehydration due to gastroenteritis in childrenCochrane Infectious Diseases Group
Jing2009Chinese herbal medicine for premenstrual syndromeCochrane Gynaecology and Fertility Group
Kwan2009Spinal immobilisation for trauma patientsCochrane Injuries Group
Kwan2006Interventions for increasing pedestrian and cyclist visibility for the prevention of death and injuriesCochrane Injuries Group
Lazzerini2016Oral zinc for treating diarrhoea in childrenCochrane Infectious Diseases Group
MacGillivray2016Lactose avoidance for young children with acute diarrhoeaCochrane Infectious Diseases Group
Majorin2019Interventions to improve disposal of child faeces for preventing diarrhoea and soil‐transmitted helminth infectionCochrane Infectious Diseases Group
Marjoribanks2015Nonsteroidal anti‐inflammatory drugs for dysmenorrhoeaCochrane Gynaecology and Fertility Group
Oltean2014Herbal medicine for low‐back painCochrane Back and Neck Group
Pérez-Gaxiola2018Smectite for acute infectious diarrhoea in childrenCochrane Infectious Diseases Group
Saragiotto2016Paracetamol for low back painCochrane Back and Neck Group
Verbeek2011Manual material handling advice and assistive devices for preventing and treating back pain in workersCochrane Back and Neck Group
Worster2012Fluids and diuretics for acute ureteric colicCochrane Kidney and Transplant Group


Limbs

AuthorYearTitleCochrane Review Group
Bleakley2012Cold‐water immersion (cryotherapy) for preventing and treating muscle soreness after exerciseCochrane Pain, Palliative and Supportive Care Group
Capstick2014Interventions for treating fingertip entrapment injuries in childrenCochrane Bone, Joint and Muscle Trauma Group
Chalmer2013Conservative interventions for treating hyperextension injuries of the proximal interphalangeal joints of the fingersCochrane Bone, Joint and Muscle Trauma Group
Derry2014Salicylate‐containing rubefacients for acute and chronic musculoskeletal pain in adultsCochrane Pain, Palliative and Supportive Care Group
Derry2015Topical NSAIDs for acute musculoskeletal pain in adultsCochrane Pain, Palliative and Supportive Care Group
Garrison2012Magnesium for skeletal muscle crampsCochrane Neuromuscular Group
Gillespie2012Interventions for preventing falls in older people living in the communityCochrane Bone, Joint and Muscle Trauma Group
Handoll2018Interventions for treating wrist fractures in childrenCochrane Bone, Joint and Muscle Trauma Group
Hawke2012Non‐drug therapies for lower limb muscle crampsCochrane Neuromuscular Group
Herbert2011Stretching to prevent or reduce muscle soreness after exerciseCochrane Bone, Joint and Muscle Trauma Group
Jones2015Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injuryCochrane Bone, Joint and Muscle Trauma Group
Lenza2016Conservative interventions for treating middle third clavicle fractures in adolescents and adultsCochrane Bone, Joint and Muscle Trauma Group
Ranchordas2017Antioxidants for preventing and reducing muscle soreness after exerciseCochrane Bone, Joint and Muscle Trauma Group
Santesso2014Hip protectors for preventing hip fractures in older peopleCochrane Bone, Joint and Muscle Trauma Group
Taylor2012Interventions for treating acute elbow dislocations in adultsCochrane Bone, Joint and Muscle Trauma Group


Bites and stings

AuthorYearTitleCochrane Review Group
Choi2019Indoor residual spraying for preventing malaria in communities using insecticide‐treated netsCochrane Infectious Diseases Group
Duperrex2009Education of children and adolescents for the prevention of dog bite injuriesCochrane Injuries Group
Enayati2007Electronic mosquito repellents for preventing mosquito bites and malaria infectionCochrane Infectious Diseases Group
FitzGerald2014Interventions for preventing the spread of infestation in close contacts of people with scabiesCochrane Work Group
Gamble2006Insecticide‐treated nets for preventing malaria in pregnancyCochrane Infectious Diseases Group
Li2013Interventions for the symptoms and signs resulting from jellyfish stingsCochrane Pain, Palliative and Supportive Care Group
Maia2018Mosquito repellents for malaria preventionCochrane Infectious Diseases Group
Pluess2010Indoor residual spraying for preventing malariaCochrane Infectious Diseases Group
Pryce2018Insecticide-treated nets for preventing malariaCochrane Infectious Diseases Group
Pryce2018Insecticide space spraying for preventing malaria transmissionCochrane Infectious Diseases Group


Poisoning

AuthorYearTitleCochrane Review Group
Avau2018First aid interventions by laypeople for acute oral poisoningCochrane Injuries Group
Chiew2018Interventions for paracetamol (acetaminophen) overdoseCochrane Hepato‐Biliary Group


Specific injuries and conditions

AuthorYearTitleCochrane Review Group
Clarke2016Compression stockings for preventing deep vein thrombosis in airline passengersCochrane Vascular Group
De Buck2019First aid glucose administration routes for symptomatic hypoglycaemiaCochrane Metabolic and Endocrine Disorders Group
Gupta2012Electric fans for reducing adverse health impacts in heatwavesCochrane Gynaecological, Neuro‐oncology and Orphan Cancer Group
Molano-Franco2019Interventions for preventing high altitude illness: Part 3. Miscellaneous and non‐pharmacological interventionsCochrane Emergency and Critical Care Group
Simancas-Racines2018Interventions for treating acute high altitude illnessCochrane Emergency and Critical Care Group
Thompson1998Pool fencing for preventing drowning of childrenCochrane Injuries Group


Allergy

AuthorYearTitleCochrane Review Group
Bauer2018Interventions for preventing occupational irritant hand dermatitisCochrane Skin Group
Head2018Saline irrigation for allergic rhinitisCochrane ENT Group


Infectious diseases

AuthorYearTitleCochrane Review Group
Awotiwon2015Zinc supplementation for the treatment of measles in childrenCochrane Acute Respiratory Infections Group
Chalumeau2013Acetylcysteine and carbocysteine for acute upper and lower respiratory tract infections in paediatric patients without chronic broncho‐pulmonary diseaseCochrane Acute Respiratory Infections Group
Chen2011Chinese medicinal herbs for measlesCochrane Acute Respiratory Infections Group
Deckx2016Nasal decongestants in monotherapy for the common coldCochrane Acute Respiratory Infections Group
Ejere2015Face washing promotion for preventing active trachomaCochrane Eyes and Vision Group
Gillies2012Positioning for acute respiratory distress in hospitalised infants and childrenCochrane Acute Respiratory Infections Group
Gould2017Interventions to improve hand hygiene compliance in patient careCochrane Effective Practice and Organisation of Care Group
Hawke2018Homeopathic medicinal products for preventing and treating acute respiratory tract infections in childrenCochrane Acute Respiratory Infections Group
Jiang2012Chinese medicinal herbs for acute bronchitisCochrane Acute Respiratory Infections Group
Karsch-Völk2014Echinacea for preventing and treating the common coldCochrane Acute Respiratory Infections Group
Kim2015Non‐steroidal anti‐inflammatory drugs for the common coldCochrane Acute Respiratory Infections Group
King2015Saline nasal irrigation for acute upper respiratory tract infectionsCochrane Acute Respiratory Infections Group
Li2013Acetaminophen (paracetamol) for the common cold in adultsCochrane Acute Respiratory Infections Group
Lissiman2014Garlic for the common coldCochrane Acute Respiratory Infections Group
Meremikwu2005Paracetamol versus placebo or physical methods for treating fever in childrenCochrane Infectious Diseases Group
Meremikwu2003Physical methods versus drug placebo or no treatment for managing fever in childrenCochrane Infectious Diseases Group
Mischke2014Gloves, extra gloves or special types of gloves for preventing percutaneous exposure injuries in healthcare personnelCochrane Work Group
Rabiu2012Environmental sanitary interventions for preventing active trachomaCochrane Eyes and Vision Group
Shaikh2014Decongestants, antihistamines and nasal irrigation for acute sinusitis in childrenCochrane Acute Respiratory Infections Group
Shu2015Chinese medicinal herbs for mumpsCochrane Acute Respiratory Infections Group
Singh2017Heated, humidified air for the common coldCochrane Acute Respiratory Infections Group
van der Wouden2017Interventions for cutaneous molluscum contagiosumCochrane Skin Group
Verbeek2016Personal protective equipment for preventing highly infectious diseases due to exposure to contaminated body fluids in healthcare staffCochrane Work Group
Weller2002Condom effectiveness in reducing heterosexual HIV transmissionCochrane HIV/AIDS Group
Wong2013Combined and alternating paracetamol and ibuprofen therapy for febrile childrenCochrane Infectious Diseases Group
Zalmanovici Trestioreanu2018Cyclamen europaeum extract for acute sinusitisCochrane Acute Respiratory Infections Group


Pregnancy and delivery

AuthorYearTitleCochrane Review Group
Aasheim2017Perineal techniques during the second stage of labour for reducing perineal traumaCochrane Pregnancy and Childbirth Group
Abedi2016Breastfeeding or nipple stimulation for reducing postpartum haemorrhage in the third stage of labourCochrane Pregnancy and Childbirth Group
Balogun2016Interventions for promoting the initiation of breastfeeding Cochrane Pregnancy and Childbirth Group
Basevi2014Routine perineal shaving on admission in labourCochrane Pregnancy and Childbirth Group
Beckmann2013Antenatal perineal massage for reducing perineal traumaCochrane Pregnancy and Childbirth Group
Bohren2017Continuous support for women during childbirthCochrane Pregnancy and Childbirth Group
Chou2013Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum periodCochrane Pregnancy and Childbirth Group
Cluett2018Immersion in water during labour and birthCochrane Pregnancy and Childbirth Group
Conde-Agudelo2016Kangaroo mother care to reduce morbidity and mortality in low birthweight infantsCochrane Neonatal Group
Dennis2014Interventions for treating painful nipples among breastfeeding womenCochrane Pregnancy and Childbirth Group
Dowswell2015Alternative versus standard packages of antenatal care for low‐risk pregnancyCochrane Pregnancy and Childbirth Group
Gupta2017Position in the second stage of labour for women without epidural anaesthesiaCochrane Pregnancy and Childbirth Group
Hodnett2012Alternative versus conventional institutional settings for birthCochrane Pregnancy and Childbirth Group
Hofmeyr2017Fundal pressure during the second stage of labourCochrane Pregnancy and Childbirth Group
Hofmeyr2013Uterine massage for preventing postpartum haemorrhageCochrane Pregnancy and Childbirth Group
Imdad2013Umbilical cord antiseptics for preventing sepsis and death among newbornsCochrane Pregnancy and Childbirth Group
Jones2012Pain management for women in labour: an overview of systematic reviewsCochrane Pregnancy and Childbirth Group
Khianman2012Relaxation therapy for preventing and treating preterm labourCochrane Pregnancy and Childbirth Group
Kobayashi2017Assessment and support during early labour for improving birth outcomesCochrane Pregnancy and Childbirth Group
Lawrence2013Maternal positions and mobility during first stage labourCochrane Pregnancy and Childbirth Group
Lemos2017Pushing/bearing down methods for the second stage of labourCochrane Pregnancy and Childbirth Group
Li2012Chinese herbal medicines for threatened miscarriageCochrane Pregnancy and Childbirth Group
Matthews2015Interventions for nausea and vomiting in early pregnancyCochrane Pregnancy and Childbirth Group
McDonald2013Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomesCochrane Pregnancy and Childbirth Group
Molakatalla2017Aspirin (single dose) for perineal pain in the early postpartum periodCochrane Pregnancy and Childbirth Group
Moore2016Early skin‐to‐skin contact for mothers and their healthy newborn infantsCochrane Pregnancy and Childbirth Group
Psaila2017Infant pacifiers for reduction in risk of sudden infant death syndromeCochrane Neonatal Group
Sibley2012Traditional birth attendant training for improving health behaviours and pregnancy outcomesCochrane Pregnancy and Childbirth Group
Singata2013Restricting oral fluid and food intake during labourCochrane Pregnancy and Childbirth Group
Sinha2015Chlorhexidine skin or cord care for prevention of mortality and infections in neonatesCochrane Pregnancy and Childbirth Group
Smith2018Massage, reflexology and other manual methods for pain management in labourCochrane Pregnancy and Childbirth Group
Smith2018Relaxation techniques for pain management in labourCochrane Pregnancy and Childbirth Group
Turawa2014Interventions for treating postpartum constipationCochrane Pregnancy and Childbirth Group
Wuytack2016Oral non‐steroidal anti‐inflammatory drugs (single dose) for perineal pain in the early postpartum periodCochrane Pregnancy and Childbirth Group
Zupan2004Topical umbilical cord care at birthCochrane Pregnancy and Childbirth Group


General pain

AuthorYearTitleCochrane Review Group
Derry2017Topical analgesics for acute and chronic pain in adults ‐ an overview of Cochrane ReviewsCochrane Pain, Palliative and Supportive Care Group
Derry2014Caffeine as an analgesic adjuvant for acute pain in adultsCochrane Pain, Palliative and Supportive Care Group
Moore2015Non‐prescription (OTC) oral analgesics for acute pain ‐ an overview of Cochrane reviewsCochrane Pain, Palliative and Supportive Care Group
Roberts2009Intercessory prayer for the alleviation of ill healthCochrane Schizophrenia Group