A Cochrane review on first aid interventions, feasible to be conducted by laypeople, in cases of acute oral poisoning, has been published in the Cochrane Library by Avau et al. This review found 24 studies, with a total of 7099 participants. All but one of these studies was conducted in a hospital setting. The majority of studies investigated the effectiveness of syrup of ipecac, a vomiting-inducing substance, and activated charcoal, an adsorbing substance. The evidence that they found was judged to be of very low certainty, which means that we are uncertain about the benefits and harms of first aid interventions for acute oral poisoning.